Shire Senior MSL II Rare Genetic Diseases: SOUTH CENTRAL in Remote, Texas

 Serve as a field-based extension of the Therapeutic Area Medical Strategy Group

 HCP related activities expected to comprise 80-95% of MSL responsibilities

 Systematically identify the scientific exchange needs of Key Opinion Leaders (KOLs), investigators and other stakeholders in patient care, establish strong professional relationships, provide credible scientific expertise and serve as a liaison to Shire Global Medical, Global Clinical and external partners

 Ensure compliant communication and education of Shire’s marketed and emerging product portfolio to meet the educational and professional needs of Shire’s key customers

 Responds effectively to requests for scientific exchange

 Support design and implementation of scientific programs with external experts and Global Medical Affairs

 Support local team disease area and product knowledge through scientific training

 Maintain personal expertise in relevant disease areas and MSL best practices

 The Manager level MSL will have additional management, leadership and project responsibilities internal and external to GMA

% of Time

Job Function and Description


KOL Relationship Management

  • Through appropriate scientific exchange, builds and maintains professional relationship with external stakeholders to expand Shire’s research, advisory and educational partnership opportunities

  • Ensures high standard of professionalism to develop and maintain “peer-to-peer” scientific relationships with key thought leaders in healthcare, academia, payer, and government organizations per strategic territory plans and as requested by KOLs, including the management of strategic scientific partnerships and scientific exchange

  • Provide scientific liaison support to Investigators currently involved in Shire’s interventional or observational studies and investigator initiated research

  • Serve as a liaison between HCPs and Shire medical affairs

  • Facilitate 1:1 and group scientific interactions with healthcare professionals

  • Participate in KOL planning

  • Maintain KOL plans and update medical customer relationship management system in a timely, accurate and compliant manner

  • Maintain awareness of and access to internal and external information sources available to support high-quality scientific exchange, and coordinate high-quality interactions between these resources and external customers


Contribute to Shire’s Strategic Medical Strategy

  • Communicates key medical insights from KOLs/HCPs to inform refinement of medical strategy

  • Gains customer insights, opinions and feedback and engages with internal colleagues to connect business opportunities with internal resources

  • Provide scientific input and participate in local medical and cross-functional initiatives

  • Provide field-based medical support to Shire’s clinical research programs, registries, and facilitation of the investigator initiated research process

  • Under the guidance of [MSL Team Lead or Region Lead] , provides scientific support for company-sponsored meetings

  • Participates on internal project teams as directed by Management


Mentoring and Project Management Activities

  • Generates new ideas and constantly searches for novel applications of development plan strategies and tactics

  • Fosters teamwork within the area to achieve strategic objectives

  • Encourages an environment leading positive performance among colleagues and internal customers, and supports both individual and overall program success

  • Is a mentor for other MSL team members

  • Assist and augment training development of regional field-based MSLs

  • Assist management with development and implementation of strategic plans and objectives; able to assist with administrative aspects of regional activities

  • Actively guides contributions of cross-functional project teams


Effective and Compliant Dissemination of Data

  • Respond within defined timeline and quality standards to unsolicited inquiries from HCPs and other stakeholders received by Global Medical Affairs and referred to GMA by other Shire functions; forwards reports of adverse events according to Shire’s policy

  • Support development of appropriate responses to unique inquiries as required, such as the presentation of scientific evidence and medical education

  • Presents clinical and disease state information to a variety of audiences, including KOLs, Medical advisors, formulary/decision makers and other HCPs

  • Ensures appropriate scientific exchange with HCPs by fostering fair and balanced medical and scientific communications that are not misleading

  • Serves as scientific resource at key medical, scientific, and patient advocacy conferences as assigned

  • Conducts therapeutic training for Sales and Medical colleagues upon request

Education and Experience Requirements

  • An advanced degree in life sciences (MD, PharmD or PhD or equivalent) is required

  • Has an established track record of effective and influential oral presentations within the healthcare profession

  • Demonstrative therapeutic research/experience or substantive patient care experience is required (3 years minimum)

  • Require minimum 36 months of experience as a field MSL

  • Demonstration of expertise in key skills, capabilities and competencies

Key Skills, Capabilities, and Competencies

  • Establishes credible and long-lasting relationships and has personal impact through engaging respectfully and professionally

  • Focus on personal accountability and ownership – constantly challenging oneself to take responsibility for continuous performance improvement and operational excellence; reliable and predictable for colleagues and customers; excellent presentation skills of scientific and medical data to small and large audiences

  • Acts on the needs of patients

  • Able to exchange scientific ideas and information openly and effectively with key opinion leaders and with colleagues

  • Demonstrates in-depth therapeutic competency and expertise of the leading science in designated disease state; maintain knowledge base and scientific expertise on all assigned Shire disease areas and products

  • Able to manage challenging conversations and handle objections

  • Focused on customer and patient needs

  • Able to work effectively on multi-disciplinary and in virtual teams

  • Effective listening skills

  • Capable of building professional relationships and focused on identifying and responsibly advancing opportunities for scientific exchange within focus disease areas

  • Ability to partner and collaborate appropriately with R&D, Commercial, and other functions

  • Superior written and verbal communication skills

  • Strong leadership and influencing skills

  • Positive attitude: Has a winning attitude and demonstrates a commitment to goals and to MSL team with a positive approach to problems, even in the face of adversity

  • Highly motivated and self-directed with ability to skillfully plan, manage and prioritize projects independently; demonstrates resilience and flexibility while planning and organizing multiple priorities

  • Develop and update knowledge of applicable pharmaceutical guidelines and regulations, including, but not limited to, ICH, GCP, PhRMA, DOJ, OIG, R&D Code of Ethical Practices and company policies

  • Above average computer skills (MS Office, databases, etc)

Complexity and Problem Solving

  • Appropriate identification, assessment, and development of relationships with KOLs

  • Appropriate assessment and allocation of available resources

  • Individual activity plan development overseen by [MSL Region or Team Lead]

  • External stakeholder management and interactions

  • Understands value of Shire’s MSL-KOL professional relationship

  • Understands value of Shire MSL-Internal stakeholders relationship

Internal and External Contacts

  • Position is accountable to the [MSL Region or Team Lead]

  • Internal Collaboration: Compliance, Legal, HR, Commercial, Global Medical Affairs, R&D

  • External: Key opinion leaders, HCPs, patient advocacy groups, regional policy makers, etc.

Other Job Requirements

  • Frequent travel is required. Availability to travel approximately 40-70% of time

  • Availability to attend meetings on holidays and weekends

  • Clean and valid driver’s license

  • Fluent in English and local territory language

Equal Employment Opportunity

Shire is an Equal Opportunity Employer committed to a diverse workforce. Shire will not discriminate against any worker or job applicant on the basis of race, color, religion, gender, national origin, ancestry, age, sexual orientation, marital or civil partnership status, pregnancy, gender reassignment, non-job related mental or physical disability, genetic information, veteran status, military service, application for military service, or membership in any other category protected under law.

EEO is the Law -

EEO is the Law – Supplement -

Pay Transparency Policy -

Reasonable Accommodations

Shire is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.