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Company Description Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion. Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career. Recognitions Consistently Ranked Science 's Top Employer Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we've been named the No. 1 company to work for in the biopharma industry in Science 's Top Employers survey for four years in a row.A Certified Great Place to Work® We believe our company is truly special, and our employees agree. In July 2024, we became Great Place to Work-certified in the U.S. for the fourth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, PEOPLE® Companies That Care, Best Workplaces for Women™, Best Workplaces for Millennials™, and Best Medium Workplaces™ lists. Overview Insmed is seeking an innovative and highly motivated Senior Scientist to support development, production, and characterization of novel AAV gene therapies at the New Jersey Research Development Labs. Responsibilities may include AAV production and purification, AAV potency testing, AAV titration, and AAV transgene construct design. Responsibilities * Produce and purify AAV gene therapy candidates. * Design and produce novel AAV transgene constructs. * Titer AAV batches. * Develop cell-based biological potency assays. * Effectively collaborate with peers within metabolic gene therapies and broader research teams to evaluate AAV gene therapy candidate properties and function. * Author and review protocols, electronic notebook entries, technical reports, and scientific publications. * Maintain proper documentation of experimental procedures and results.Qualifications: * Minimum Ph.D. degree in biological sciences discipline and 2+ years of relevant industry experience. * Expert knowledge and hands-on experience in research-scale high-throughput AAV production and purification required. * Expert knowledge and hands-on experience with AAV titration required. * Expert knowledge and hands-on experience with mammalian cell culture required. * Expert knowledge and hands-on experience with in vitro assay development required. * Expert knowledge and hands-on experience with standard molecular biology techniques required. * Entrepreneurial spirit, proactive problem-solving attitude, and strong willingness to take on new challenges a must. * Excellent organizational and time management skills required. * Excellent verbal and written communication skills required. * Knowledge of immunology a plus. * Experience with flow cytometry a plus. * Experience with in vivo work a plus.#LI-MM1 Salary Range $115,000 - $161,867 a year Compensation & Benefits We're committed to investing in every team member's total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including: * Flexible approach to where and how we work, regionally based * Competitive compensation package including bonus * Stock options and RSU awards * Employee Stock Purchase Plan (ESPP) * Flexible Vacation Policy * Generous paid holiday schedule and winter break ADDITIONAL U.S. BENEFITS: * 401(k) plan with company match * Medical, dental, and vision plans * Company-provided Life and Accidental Death & Dismemberment (AD&D) insurance * Company-provided short and long-term disability benefits * Unique offerings of pet, legal, and supplemental life insurance * Flexible spending accounts for medical and dependent care * Accident and Hospital Indemnity insurance * Employee Assistance Program (EAP) * Mental Health on-line digital resource * Well-being reimbursement * Paid leave benefits for new parents * Paid time off to volunteer * On-site, To view the full job description, click here