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This job was posted by https://illinoisjoblink.illinois.gov : For more information, please see: https://illinoisjoblink.illinois.gov/jobs/11881478 Department

BSD PED - Hematology, Oncology, and Stem Cell Transplantation - LaBelle Lab

About the Department

Section of Pediatric Hematology/Oncology provides care for patients and families with acute and chronic medical conditions, or other hematologic diseases, requiring specialized knowledge and skills in Hematology, Oncology, and Stem Cell Transplantation.

Job Summary

Under the direction of the principal investigator, the candidate will perform moderately complex lab and research-related duties and tasks. Provide technical and administrative support in an exciting research program designed to understand the fundamental mechanisms of cell death in cancerous cells and activated lymphocytes and to develop new therapeutic strategies to combat therapeutic resistance. The laboratory uses cell culture and mouse models to recapitulate human disease with a clear goal for clinical translation. May work with, orient, or coordinate with the work of other research support staff and students.

The major goal of the LaBelle laboratory is to dissect and pharmacologically target intracellular proteins to induce cancer cell death and manipulate the immune response. We are currently applying new research tools and prototype therapeutics that we, and others, have developed to target the BCL-2 family of proteins and other cell signaling proteins in immune cells.

A large part of our lab also focuses on using portions of the actual proteins, or peptides, as drugs and biological tools to uncover specific molecular pathways in diseased and normal cells. Peptide-based therapeutics have enormous potential for immune modulation and direct cancer treatment but have traditionally lacked efficient stabilization and delivery within patients, and thereby, have had limited clinical applications. We are working to overcome these barriers within the lab and through collaboration with nanotechnologists and chemical engineers.

Overall, we are committed to the translation of our findings to pediatric and adult patients with cancer and immune system disease. While performing research at the University of Chicago, we are in close proximity to scientists, clinicians, and patients and are deeply committed to working collaboratively with these groups to make significant inroads in treating those suffering from a refractory disease.

This position is wholly funded by contractual grant funding which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.

Responsibilities

• Maintenance of human cancer cell lines, cell death assays, flow cytometry, PCR, in vitro drug testing, and light-field/confocal microscopy.
• Breeding and care for mice in treatment studies, including blood draws, injections, and necropsies.
• Collecting and maintaining data and/or specimens.
• Collects and enters data; assists in analysis of data and with preparation of reports, manuscripts, and other documents.
• Maintaining and ordering equipment and supplies.
• Translational work may include monitoring compliance with institution, state, and federal regulatory policies, procedures, directives, and mandates.
• Assisting with developing data collection tools, assisting with building databases, and providing general administrative support.
• This job provides technical and administrative support in a laboratory environment performing basic laboratory techniques, research, and analysis under direction.
• Provides routine or standardized laboratory duties by collecting data in support of research projects under direct supervision.
• Complies with institutional, state, and federal egulatory policies, procedures, directives, and mandates.
• Performs other related work as needed.

Minimum Qualifications

Education:

Minimum requirements include vocational training, apprenticeships or the equivalent experience in related field (not typically required to have a four-year degree).

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Work Experience:

Minimum requirements include knowledge and skills developed through ---

Certifications:

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Preferred Qualifications

Education:

• Bachelor\'s degree in a field relevant to the research being conducted.

Experience:

• One year of relevant research experience.

Preferred Competencies

Knowledge of research techniques or methods.

Knowledge of regulatory policies and procedures.

Analytical skills.

Problem-solving skills.

Attention to detail.

Organizational skills.

Verbal and written communication skills.

Ability to work independently and as part of a team.

Knowledge of Microsoft Office.