Job Information
Actalent Sr. Research Associate in Doylestown, Pennsylvania
Description:
This is an opportunity to join a small, entrepreneurial, and well-funded biotech company. Building on research breakthroughs from an internationally renowned scientific team. We are searching for an experienced Senior Research Associate with advanced laboratory skills in virology and cellular and molecular biology. A great interest in drug discovery and cutting-edge science is essential for this position.
• Propagate BSL-2+ level viruses and cell lines for evaluation of candidate drugs
• Perform standard analyses of cell growth properties and viral replication
• Perform routine screening of candidate drugs in high-throughput plate formats (96, 384-well)
• Perform advanced molecular and cell biological analyses of viral and cellular targets of candidate drugs including signal transduction assays of observed antiviral effects
• Develop new viral, cellular and molecular assays as needed, validating reproducibility, sensitivity, and dynamic range to establish utility and appropriateness for comparative drug profiling
• Demonstrate rigor in assay optimization and compound profiling with objective to support medicinal chemistry efforts to optimally rank compounds and select drugs going into the clinic to treat patients
Skills:
Cell culture, Biology, Molecular biology, Pcr, Assay, Development, virology, virus, western blot, DNA, dna sequencing, dna extraction, RNA, viral transduction, tissue culture, assay development
Additional Skills & Qualifications:
• 7+ years of laboratory work and industry experience with proven ability to independently design, troubleshoot, and successfully execute experiments with proper controls for interpretation
• Master’s degree (or Bachelor’s degree with equivalent experience) in Virology, Immunology, Microbiology or related biological sciences
• Efficient BSL2+ tissue culture techniques of mammalian cell lines, virus propagation, titration
• Demonstrated independent expertise in molecular biology techniques including DNA and RNA manipulation, PCR, cloning, transfection, virus transduction
• Demonstrated independent expertise in cellular protein analyses techniques (e.g., Western blot, immunoprecipitation, immunofluorescence)
Experience Level:
Expert Level
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
Hiring diverse talent
Maintaining an inclusive environment through persistent self-reflection
Building a culture of care, engagement, and recognition with clear outcomes
Ensuring growth opportunities for our people
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.