Shire Jobs

Computational Scientist – (Machine Learning)

• Location: Cambridge, UK

About the job

In alignment to our digital transformation, we have launched a new major strategic initiative in 2023: the Biologics x AI Transformation. This is positioned to be a unique data-driven team, with expertise in AI platforms, data engineering, ML operations, data science, computational biology, strategy, and beyond. We are working as one to identify, design, and scale state-of-the-art AI capabilities targeted to truly transform how we research biologics.

You are a dynamic Computational Scientist who will work with other scientists to apply cutting-edge computation, Machine Learning/Deep Learning approaches to revolutionize our large molecule computational tools by contributing to accelerating and improving the process of design and engineering of novel biologics drug candidates.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main responsibilities:

• Apply and develop artificial intelligence and machine learning (AI/ML) approaches (e.g. classification, clustering, machine learning, deep learning) on pharma research data sets (e.g. activity, function, ADME properties, physico-chemical properties, etc.).

• Building models from internal and external data sources, algorithms, simulations, and performance evaluation by writing code and using state-of-the art machine learning technologies.

• Close interactions with other Computational scientists, data engineers, software engineers, UX designers, as well as research scientists in core scientific platforms focusing on protein therapeutics, in an international context (US, Europe).

• Update and report relevant results to interdisciplinary project teams and stakeholders.

About you:

• PhD in a field related to AI/ML or Data Analytics such as: Computer Science, Mathematics, Statistics, Physics, Biophysics, Computational Biology or Engineering Sciences.

• Ideally 1+ years of industry experience, new grads will also be considered. Should have a track record of applying ML/Deep Learning (DL) approaches to solve molecule-related problems.

• Familiarity with protein structure or sequence featurization/embeddings.

• Familiarity with advanced statistics, ML/DL techniques including various network architectures (CNNs, GANs, RNNs, Auto-Encoders, Transformers, PLM etc.), regularization, embeddings, loss-functions, optimization strategies, or reinforcement learning techniques.

• Proficiency in Python and deep learning libraries such as PyTorch, TensorFlow, Keras, Scikit-learn, Numpy, Matpilotlib.

• Familiarity with data visualization and dimensionality reduction algorithms.

• Ability to develop, benchmark and apply predictive algorithms to generate hypotheses.

• Comfortable working in cloud and high-performance computational environments (e.g. AWS).

• Excellent written and verbal communication, strong tropism for teamwork.

• Strong understanding of pharma R&D process is a plus.

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Pursue Progress . Discover Extraordinary .

Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together.

Visas for those who do not already have the right to work in the UK will be considered on a case by case basis according to business needs and resources.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.

Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) !

#LI-EUR

Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) !

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo)

As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live.

All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)