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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$121,500 - $198,000

This position is within the Lead Optimization Team of BioTDR organization. We are responsible for generating, characterizing, and optimizing biotherapeutics from lead generation to lead optimization and preclinical development. We are searching for a highly motivated and creative scientist to join a talented, multidisciplinary team. This position provides an outstanding opportunity to transform ideas from concept to clinical development.

Responsibilities

• Optimization of bioconjugation across modalities (e.g. conjugation of small molecules, peptides, oligonucleotides to proteins and antibodies)

• Optimization of bioconjugate function and delivery (e.g. increasing potency, pharmacokinetics, efficacy, and tissue selectivity)

• Characterizing protein and conjugate structure, stability, and solution properties using various biochemical and biophysical approaches.

• Development of companion in vitro cell-based assays to characterize molecule properties and functional activities

• Effectively collaborate and communicate across diverse stakeholder groups

• Develop innovative approaches to unlock new avenues of research and accelerate the progress of projects and platforms

Basic Qualifications

• PhD in biochemistry, protein chemistry, or related field. OR

• MS in related field and 5+ years of relevant industrial experience.

Additional Skills and Preferences

• Hands-on experience in protein purification, bioconjugation, and characterization of proteins and conjugates in academic or industrial settings.

• Strong core proficiency in protein biochemistry, knowledge of protein structure-function relationship, and experience in biochemical analyses

• Strong preference for ability to develop and perform cell-based assays.

• Demonstrated self-initiative and appropriate risk-taking behaviors.

• Exceptional problem solving and decision-making skills.

• Demonstrated ability to work productively and collaboratively in an interdisciplinary and fast-paced team environment.

• Demonstrated ability to prioritize multiple activities and thrive in a setting that requires comfort with ambiguity.

• An active scientific curiosity and interest for complementary disciplines within the pharmaceutical industry.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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