Shire US Forecasting Manager in Lexington, Massachusetts

Reporting to the US Forecasting Lead, the US Forecasting Manager will play a key support role in developing and communicating US forecasts across 5 Shire franchises and numerous inline and pipeline products. The Forecasting Manager will review existing forecast methodologies and help develop recommendations around a Shire best practice for multiple types of therapies (e.g., specialty, rare, oncology). Individual will liaise with key stakeholders in marketing, finance, patient services, and market access to ensure the latest thinking is incorporated into each product’s forecasting assumptions and signed off by respective owners. Manager will play a role in presenting forecast results at key planning sessions such as budget planning, current year planning, long range planning and supply/manufacturing & TechOps reviews.

Forecasting Manager will possess a strong combination of technical, problem solving, communication, and interpersonal skills.


% of Time

Job Function and Description


Forecasting tool development and maintenance .

Manager will help assess existing forecasting models across 5 franchises, and prioritize areas for improvement. Manager will design and build improved tools (with or without support from vendors) to meet customized needs of each franchise, using 80/20 approach focusing on critical needs first. Balance of standardization and customization will be sought.


Forecast updates and reviews .

Forecasting Manager will refresh models with latest actuals at the product or patient level as they become available. Manager must be comfortable with various types of sales audit data such as NDTI, NSP, NPA, Xponent, as well as patient hub (within Shire) and specialty pharmacy (SP) data. Individual will also work closely with franchise teams and other stakeholders to incorporate latest thinking in forecast assumptions such as launch timing, patent expiry, and competitive entry. These assumptions will be used to create most likely forecast, a key input to various commercial and financial planning exercises such as monthly latest views (LVs), annual budgets, and long-range planning (LRP). Manager will oversee repository of product forecasts and help create simple, standardized output tools for fast, clear communication to key stakeholders. Manager will also play a role in official forecast readouts with senior management.

In addition to regular forecast updates and reviews Manager will assist Lead in responding to ad hoc scenario requests related to business development and other strategic initiatives.


Product performance tracking .

Manager will work with Lead to identify fit-for-purpose tracking techniques for each product and franchise as needed. Individual will work with other functions such as Commercial Operations to ensure tracking needs are met, while synergies are leveraged and redundancies are minimized.

Education and Experience Requirements

BS/BA required.

MBA preferred.

4+ years of business experience in the Pharmaceutical and/or Biotech industry with substantial experience in business analysis and forecasting; extensive knowledge of secondary research methodologies and Pharma industry databases. Understanding of relevant data sets (claims, national/subnational IMS, patient services, etc.). Additional industry experience in product development, marketing and sales considered a plus. Experience in a matrix business environment also a plus.

Key Skills, Abilities, and Competencies

Interpersonal and Technical

  • Strong interpersonal skills with the ability to liaise with multiple business partners

  • Self-confidence, initiative and ability to work independently in order to meet deadlines

  • Advanced technical skills in Microsoft Excel and PowerPoint.

  • Familiarity with forecasting software such as Forecast Pro, Crystal Ball, @Risk, etc.

Complexity and Problem Solving

  • Objective, critical thinking with focus on getting to the right answer, in a clear, concise way

  • Strong attention to detail, and the ability to “sense check” numbers prior to review w/stakeholders

  • Identifies important trends and makes recommendations

  • Is able prioritize in the face of competing demands

Builds the Narrative

  • Identifies the proper visual way to depict data to support and articulate message

  • States and clarifies assumptions

  • Ability to move from ground level to 30K feet, articulating the “so what” behind the numbers

D rives Innovation

  • Contributes to breakthrough solutions

  • Draws on unexpected or seemingly unrelated ways of thinking

  • Operates from a framework of possibility

  • Supports creation of a best-in-class forecasting function.

Internal and External Contacts

Internal: US Commercial Leadership, Franchise Finance Business Partners, Market Insights & Analytics Teams, Commercial Operations, Global Product Strategy (GPS), GPS Finance, Supply Chain, Regulatory, Tech Ops and Legal

External : Data suppliers; external forecasting, market research, and competitive intelligence consultants

Other Job Requirements

US Travel: 5-10%

Notice to Employment / Recruitment Agents:

Employment / Recruitment agents may only submit candidates for vacancies only if they have written authorization to do so from Shire’s Talent Acquisition department. Any agency candidate submission may only be submitted to positions opened to the agency through the specific Agency Portal. Shire will only pay a fee for candidates submitted or presented where there is a fully executed contract in place between the Employment / Recruitment agents and Shire and only if the candidate is submitted via the Agency Portal. Candidates submitted or presented by Employment / Recruitment Agents without a fully executed contract or submitted through this site shall not be deemed to form part of any Engagement for which the Agency may claim remuneration.

Equal Employment Opportunity

Shire is an Equal Opportunity Employer committed to a diverse workforce. Shire will not discriminate against any worker or job applicant on the basis of race, color, religion, gender, national origin, ancestry, age, sexual orientation, marital or civil partnership status, pregnancy, gender reassignment, non-job related mental or physical disability, genetic information, veteran status, military service, application for military service, or membership in any other category protected under law.

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Reasonable Accommodations

Shire is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.