Shire Manufacturing Supervisor (Chromatography Column Packing) in Neuchatel, Switzerland

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmic, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology. In 2016, Shire grew its organization to approximately 23,000 employees+ globally, following integrations of Dyax and Baxalta.

An exciting and challenging opportunity has become available at Shire Neuchâtel Plant (approx. 650 employees) for an experienced Manufacturing Operational Support Supervisor to join our Manufacturing support team.

This is an exciting career opportunity for a dynamic, autonomous, continuous improvement minded and change agile manufacturing professional to embrace a team-based culture and more specifically within the manufacturing teams within a world-class Biotech manufacturing environment.

Job summary

Within the Manufacturing support department, reporting to the Head of Manufacturing support group, the purpose of this role is to be supervisor of the team in charge of transversal manufacturing activities, i.e. column packing, inoculum steps and sampling for environmental monitoring within the production department. The main aspects of this position are focused on people management and development, respect of applicable procedures and requirements, promotion and deployment of continuous improvement culture, definition of priorities within the group in accordance with the production planning and development of synergies with production units.

Essential duties and responsibilities

  • Provide feedback to the team and focus on team development

  • Promote, participate and launch manufacturing process improvement and/or enhancement projects

  • Define and develop synergies with the production units

  • Drive execution of the transversal manufacturing activities, including column packing, inoculum steps and sampling for environmental monitoring.

  • Drive metrics related to the activities of the team and provide regularly analysis and actions to the Manufacturing leadership team and to the floor

  • Provide day-to-day work direction, expertise and coaching to the team in order to meet the production priorities in a safe, timely, costly and quality manner

  • Review and align team priorities with planning department, production units, QC and QA as required

  • Ensure appropriate management of the packed (in-use and back-up) columns for the different production units and of the chromatography resins inventory in collaboration with the planning department

  • Drive initiatives to ensure standardization, optimization and consistency of processes and documentation related to the different activities of the group

  • Actively participate or ensure his/her team participates in problem solving and deviation handling

  • Act as a Subject Matter Expert (SME) if needed and support/coach production team during internal and external audits for selected topics

  • Incorporate and ensure respect of cGMP concepts (Good Manufacturing Practices) and EHS requirements

Qualifications

  • Very strong knowledge and interest in manufacturing operations, associated processes and documentation.

  • Ability to think, take initiatives and act cross-functionally, interacting with EHS, QA, QC, engineering, project departments, etc...

  • Ability to work in a fast, dynamic and diverse business environment with a high emphasis on achieving results

  • Good leadership and interpersonal skills, self-motivated, structured, capable of analyzing complex situations through innovative thought and experience, strong decision-making skills

  • Good planning and anticipation skills, ability to develop long-term vision and to see the “big picture”

  • Ability to supervise different types of activities, with appropriate prioritization in order to ensure deadlines are met in timely, costly and quality manner

  • Strong focus on customer service, standardization and continuous improvement

  • Ability to work well and develop relationships with all levels of internal management, with the team and with the partners within and outside production department

  • Good communication skills, can adapt style to the audience.

  • Excellent team player prepared to work in, and embrace a team-based culture and more specifically within the manufacturing teams

  • Fluent in English and French

Education & Experience

  • Bachelor/Master’s degree and minimum 5-8 years of experience within a biotech/pharmaceutical manufacturing environment (Process Operations, Engineering or Quality)

  • Ideally demonstrated experience in people management, and technical knowledge in column packing and in Neuchâtel production units processes

  • Expertise in Quality/Compliance within an FDA regulated/GMP manufacturing field

Working Environment:

  • While this is a day-time job, must be able to work on occasions in controlled environments (ISO 5, ISO 7 and ISO 8 environments ; grade A, B, and C) requiring special gowning. Will be required to follow gowning requirements and wear protective clothing over the head, face, hands, feet and body.

Living our leadership behaviors is a basic expectation for all Shire employees. Shire expects all employees to embody the following:

  • Be Positive

  • Be Accountable

  • Be Results Oriented

  • Be An Excellent Manager of Self and Others

Notice to Employment / Recruitment Agents:

Employment / Recruitment agents may only submit candidates for vacancies only if they have written authorization to do so from Shire’s Talent Acquisition department. Any agency candidate submission may only be submitted to positions opened to the agency through the specific Agency Portal. Shire will only pay a fee for candidates submitted or presented where there is a fully executed contract in place between the Employment / Recruitment agents and Shire and only if the candidate is submitted via the Agency Portal. Candidates submitted or presented by Employment / Recruitment Agents without a fully executed contract or submitted through this site shall not be deemed to form part of any Engagement for which the Agency may claim remuneration.

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.