Job Information
J&J Family of Companies Senior Scientist, Biophysics in Spring House, Pennsylvania
Johnson & Johnson is recruiting for a Senior Scientist, Biophysics located in Spring House, PA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
At Johnson & Johnson, we all belong.
The Biophysics group within Biologics Discovery is committed to the delivery of high-quality drug candidates. The Senior Scientist position offers an exciting opportunity to join the team involved in developing and applying innovative technologies to characterize biophysical attributes of molecules throughout the discovery process, from initial hit generation to lead molecule selection. This role will specifically focus on the real-time characterization of interactions with cell surface targets, as well as determining epitope diversity and high throughput binding studies.
Key Responsibilities:
Design and perform real-time interaction cytometry assays to determine binding to cell surface targets.
Perform SPR-based epitope binning assays.
Conduct SPR binding analysis to determine binding and activity properties.
Independently interpret and communicate the results to program teams and management.
Design and implement new techniques and strategies to study biophysical characteristics of assets and to optimize the Biophysics characterization workflow.
Function as a project team representative for the Biophysics group.
Qualifications
Education:
- Ph. D. in Cell Biology, Biochemistry, Biophysics, Structural Biology, Pharmaceutical Sciences, or other related fields with a minimum of 0-3 years postdoctoral experience or a minimum of 8-10 years of experience performing progressively advanced duties beyond a B.S. degree.
Experience and Skills:
Required:
Deep understanding of cell biology and hands on experience with cell culture is required.
Deep understanding and hands on experience characterizing biomolecules using SPR techniques is required.
Expertise in characterization of interactions with cell surface targets/membrane proteins is required.
Preferred:
- Solid understanding of the fundamentals of antibody structure and function is desired.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.