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To drive the creation of new innovative biomanufacturing solutions, Sartorius has formed an initiative to discover new trends and cutting-edge opportunities for rapid conversion towards next generation continuous and integrated closed manufacturing solutions. This exciting initiative enables the research, process development and clinical production of novel modalities using next generation manufacturing platforms, in partnership with key customers.

Sartorius’ Process Development Services team in the Greater Boston (MA) area is a part of Corporate Research Group and is engaged in the design, development, and optimization of cell and gene therapy manufacturing processes that can be transformed from early pre-clinical stage into cGMP ready manufacturing scale. The incumbent is expected to work closely together with an internal multi-disciplinary product development team, to create forward looking processes that provide a basis for commercial manufacturing that can be integrated into our process solution offering. 

What you will accomplish together with us

• You will develop, and scale-up genetic cargo delivery for cell therapy manufacturing processes for multiple modalites including immune cells, iPSCs, vector packaging cell lines

• Establish critical process parameters that enable successful process scale-up

• You will identify critical quality attributes for successful production and develop assays to measure these CQAs

• Lead multiple high impact internal and external research projects by establishing priorities, milestones, schedules, and deadlines.

• Develop and write process development proposals, conduct hands-on laboratory work to optimize and troubleshoot upstream and downstream manufacturing processes for novel LNP formulations

• Responsible for writing, reviewing, and maintaining electronic lab notebooks with the highest level of research integrity.

• Responsible for writing project reports, briefs, protocols and making presentations to internal and external partners and project teams as required.

• Participate in technology transfer activities to internal and external collaborators.

• Support marketing efforts by writing technical briefs, application notes and peer reviewed publications, leading or assisting with technical presentations at scientific conferences.

• Conduct technical investigations and risk assessments related to manufacturing processes.

• Support generation of protocols, work instructions, batch records and reports.

• Work independently in a matrixed environment.

• Perform occasional extended hours and weekends to support ongoing lab activities as needed.

• Mentor and support junior staff and build a culture of support and collaboration.

• Comply with all site policies such as record retention, ISO requirements, and accountable for good housekeeping in all laboratories.

• Comply with biohazard, special clean room and site safety/health procedures and guidelines as required.

• Assist other team members and site management team with miscellaneous duties when requested.

What will convince us

• MS (with 2+ years of industry experience) or PhD in chemical, biochemical or biomedical engineering, engineered cell therapies or related field.

• Knowledge of current developments in genome editing and gene delivery technologies.

• Experience & knowledge of state-of the-art upstream and downstream technologies for cell therapy process development workflows.

• Ability to interface with specialists from target biological application areas and engineering disciplines such as mechanical (hardware, fluidic, thermal), electrical, software, sensor technology (optical, electronical), and chemical.

• Experience working as part of collaborative R&D project team.

• Strong analytical and mathematical ability.

• Ability to work independently and constructively in a team environment.

• Must have strong personal initiative and be result oriented.

• Strong troubleshooting skills

• Strong written and verbal English communication skills, capable of clearly expressing technical concepts to people with various levels of technical expertise and diverse cultural backgrounds.

• Identification with our core values: Sustainability, Openness, Enjoyment

• Working Conditions/Environment (ex. Any irregular or unusual work schedules, travel, etc):

Travel 10-20% of time, both foreign and domestic. Work on weekends as required. Work in a Biosafety Level 2 Laboratory.

What We Offer

As a growing global life science company, with our stock listed on the German DAX and TecDAX , Sartorius offers a wide range of benefits: Personal and Professional Development: Mentoring, leadership programs, LinkedIn Learning, internal seminar offerings Worklife Balance: Paid vacation, sick time, corporate holidays and community service day; as well as flexible work schedules Making an Impact Right from the Start: Comprehensive onboarding, including a virtual online platform Welcoming Culture: Mutual support, team spirit and international collaboration; communities on numerous topics such as “Coaching”, “Agile Working” and a “Businesswomen’s Network” Health & Well Being: Wide selection of health and well-being support such as a variety of medical plans to choose from, dental, vision, EAP, and other wellness programs. Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.

Retirement Savings Plan: 401 k (with generous company match) Flexible Spending: HSA, FSA (dependent care & healthcare spending), Transportation Commuter Account Company Paid Benefits: Basic Life Insurance, AD&D, EAP, Family Planning & Women’s Health, Health Advocate Additional/Optional: Supplemental Life Insurance (employee, spouse & dependents), Legal Services, LTD & STD, Critical Illness Insurance, Student Loan Tuition Refinance Service

All qualified applicants will be considered for employment without regard to race, color, religion, sex or national origin. We are also an equal opportunity employer of individuals with disabilities and protected veterans.

Please view equal employment opportunity posters provided by OFCCP here (https://www.dol.gov/agencies/ofccp/posters) .

E-Verify Participation Info (https://www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.pdf)

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Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment. Join our global team and become part of the solution. We are looking forward to receiving your application.

We look forward to receiving your application.

www.sartorius.com/career

Sartorius is an Equal Opportunity/Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.

All employment decisions are based on valid job-related requirements.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by calling +1 631 254 4249 ext 8330 or via e-mail at accommodationrequest@sartorius.com

About Sartorius

Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide.

We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.

Join our global team and become part of the solution. We are looking forward to receiving your application. www.sartorius.com/careers